GrippeFranceV1, Main, Exploration, bibRecord, 000012

Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.

Identifieur interne : 000012 ( Main/Exploration ); précédent : 000011; suivant : 000013

Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.

Auteurs : Amélie Chastagner [France] ; Emilie Bonin [France] ; Christelle Fablet [France] ; Stéphane Quéguiner [France] ; Edouard Hirchaud [France] ; Pierrick Lucas [France] ; Stéphane Gorin [France] ; Nicolas Barbier [France] ; Véronique Béven [France] ; Emmanuel Garin [France] ; Yannick Blanchard [France] ; Nicolas Rose [France] ; Séverine Hervé [France] ; Gaëlle Simon [France]

Source :

Veterinary research [ 1297-9716 ] ; 2019.

RBID : pubmed:31590684

Descripteurs français

KwdFr :
- Animaux (MeSH), France (MeSH), Maladies des porcs (virologie), Sous-type H1N1 du virus de la grippe A (génétique), Sous-type H1N1 du virus de la grippe A (physiologie), Sous-type H1N2 du virus de la grippe A (génétique), Sous-type H1N2 du virus de la grippe A (physiologie), Sous-type H3N2 du virus de la grippe A (génétique), Sous-type H3N2 du virus de la grippe A (physiologie), Suidae (MeSH), Sus scrofa (MeSH), Virus recombinants (physiologie).
MESH :
- génétique : Sous-type H1N1 du virus de la grippe A, Sous-type H1N2 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A.
- physiologie : Sous-type H1N1 du virus de la grippe A, Sous-type H1N2 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Virus recombinants.
- virologie : Maladies des porcs.
- Animaux, France, Suidae, Sus scrofa.
Wicri :
- geographic : France.

English descriptors

KwdEn :
- Animals (MeSH), France (MeSH), Influenza A Virus, H1N1 Subtype (genetics), Influenza A Virus, H1N1 Subtype (physiology), Influenza A Virus, H1N2 Subtype (genetics), Influenza A Virus, H1N2 Subtype (physiology), Influenza A Virus, H3N2 Subtype (genetics), Influenza A Virus, H3N2 Subtype (physiology), Reassortant Viruses (physiology), Sus scrofa (MeSH), Swine (MeSH), Swine Diseases (virology).
MESH :
- geographic : France.
- genetics : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H1N2 Subtype, Influenza A Virus, H3N2 Subtype.
- physiology : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H1N2 Subtype, Influenza A Virus, H3N2 Subtype, Reassortant Viruses.
- virology : Swine Diseases.
- Animals, Sus scrofa, Swine.

Abstract

This report describes the detection of a triple reassortant swine influenza A virus of H1_avN2 subtype. It evolved from an avian-like swine H1_avN1 that first acquired the N2 segment from a seasonal H3N2, then the M segment from a 2009 pandemic H1N1, in two reassortments estimated to have occurred 10 years apart. This study illustrates how recurrent influenza infections increase the co-infection risk and facilitate evolutionary jumps by successive gene exchanges. It recalls the importance of appropriate biosecurity measures inside holdings to limit virus persistence and interspecies transmissions, which both contribute to the emergence of new potentially zoonotic viruses.

DOI: 10.1186/s13567-019-0699-y
PubMed: 31590684
PubMed Central: PMC6781375

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000010
to stream Main, to step Curation: 000010

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.</title>
<author><name sortKey="Chastagner, Amelie" sort="Chastagner, Amelie" uniqKey="Chastagner A" first="Amélie" last="Chastagner">Amélie Chastagner</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bonin, Emilie" sort="Bonin, Emilie" uniqKey="Bonin E" first="Emilie" last="Bonin">Emilie Bonin</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>INRA, US 1426, GeT-PlaGe, 24 chemin de borde rouge - Auzeville, CS 52627, 31326, Castanet-Tolosan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>INRA, US 1426, GeT-PlaGe, 24 chemin de borde rouge - Auzeville, CS 52627, 31326, Castanet-Tolosan</wicri:regionArea>
<placeName><region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
<settlement type="city">Castanet-Tolosan</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fablet, Christelle" sort="Fablet, Christelle" uniqKey="Fablet C" first="Christelle" last="Fablet">Christelle Fablet</name>
<affiliation wicri:level="3"><nlm:affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Queguiner, Stephane" sort="Queguiner, Stephane" uniqKey="Queguiner S" first="Stéphane" last="Quéguiner">Stéphane Quéguiner</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hirchaud, Edouard" sort="Hirchaud, Edouard" uniqKey="Hirchaud E" first="Edouard" last="Hirchaud">Edouard Hirchaud</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lucas, Pierrick" sort="Lucas, Pierrick" uniqKey="Lucas P" first="Pierrick" last="Lucas">Pierrick Lucas</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gorin, Stephane" sort="Gorin, Stephane" uniqKey="Gorin S" first="Stéphane" last="Gorin">Stéphane Gorin</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barbier, Nicolas" sort="Barbier, Nicolas" uniqKey="Barbier N" first="Nicolas" last="Barbier">Nicolas Barbier</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Beven, Veronique" sort="Beven, Veronique" uniqKey="Beven V" first="Véronique" last="Béven">Véronique Béven</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Garin, Emmanuel" sort="Garin, Emmanuel" uniqKey="Garin E" first="Emmanuel" last="Garin">Emmanuel Garin</name>
<affiliation wicri:level="3"><nlm:affiliation>Animal Health Service, Coop de France, 43 Rue Sedaine, 75538, Paris cedex 11, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Animal Health Service, Coop de France, 43 Rue Sedaine, 75538, Paris cedex 11</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Operational Team, ESA Platform, 31 Avenue Garnier, 69007, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Operational Team, ESA Platform, 31 Avenue Garnier, 69007, Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>GDS-France, 37 Rue de Lyon, 75012, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>GDS-France, 37 Rue de Lyon, 75012, Paris</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blanchard, Yannick" sort="Blanchard, Yannick" uniqKey="Blanchard Y" first="Yannick" last="Blanchard">Yannick Blanchard</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rose, Nicolas" sort="Rose, Nicolas" uniqKey="Rose N" first="Nicolas" last="Rose">Nicolas Rose</name>
<affiliation wicri:level="3"><nlm:affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herve, Severine" sort="Herve, Severine" uniqKey="Herve S" first="Séverine" last="Hervé">Séverine Hervé</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Simon, Gaelle" sort="Simon, Gaelle" uniqKey="Simon G" first="Gaëlle" last="Simon">Gaëlle Simon</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France. gaelle.simon@anses.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France. gaelle.simon@anses.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2019">2019</date>
<idno type="RBID">pubmed:31590684</idno>
<idno type="pmid">31590684</idno>
<idno type="doi">10.1186/s13567-019-0699-y</idno>
<idno type="pmc">PMC6781375</idno>
<idno type="wicri:Area/Main/Corpus">000010</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000010</idno>
<idno type="wicri:Area/Main/Curation">000010</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000010</idno>
<idno type="wicri:Area/Main/Exploration">000010</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.</title>
<author><name sortKey="Chastagner, Amelie" sort="Chastagner, Amelie" uniqKey="Chastagner A" first="Amélie" last="Chastagner">Amélie Chastagner</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bonin, Emilie" sort="Bonin, Emilie" uniqKey="Bonin E" first="Emilie" last="Bonin">Emilie Bonin</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>INRA, US 1426, GeT-PlaGe, 24 chemin de borde rouge - Auzeville, CS 52627, 31326, Castanet-Tolosan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>INRA, US 1426, GeT-PlaGe, 24 chemin de borde rouge - Auzeville, CS 52627, 31326, Castanet-Tolosan</wicri:regionArea>
<placeName><region type="region" nuts="2">Occitanie (région administrative)</region>
<region type="old region" nuts="2">Midi-Pyrénées</region>
<settlement type="city">Castanet-Tolosan</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fablet, Christelle" sort="Fablet, Christelle" uniqKey="Fablet C" first="Christelle" last="Fablet">Christelle Fablet</name>
<affiliation wicri:level="3"><nlm:affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Queguiner, Stephane" sort="Queguiner, Stephane" uniqKey="Queguiner S" first="Stéphane" last="Quéguiner">Stéphane Quéguiner</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hirchaud, Edouard" sort="Hirchaud, Edouard" uniqKey="Hirchaud E" first="Edouard" last="Hirchaud">Edouard Hirchaud</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lucas, Pierrick" sort="Lucas, Pierrick" uniqKey="Lucas P" first="Pierrick" last="Lucas">Pierrick Lucas</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gorin, Stephane" sort="Gorin, Stephane" uniqKey="Gorin S" first="Stéphane" last="Gorin">Stéphane Gorin</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barbier, Nicolas" sort="Barbier, Nicolas" uniqKey="Barbier N" first="Nicolas" last="Barbier">Nicolas Barbier</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Beven, Veronique" sort="Beven, Veronique" uniqKey="Beven V" first="Véronique" last="Béven">Véronique Béven</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Garin, Emmanuel" sort="Garin, Emmanuel" uniqKey="Garin E" first="Emmanuel" last="Garin">Emmanuel Garin</name>
<affiliation wicri:level="3"><nlm:affiliation>Animal Health Service, Coop de France, 43 Rue Sedaine, 75538, Paris cedex 11, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Animal Health Service, Coop de France, 43 Rue Sedaine, 75538, Paris cedex 11</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Operational Team, ESA Platform, 31 Avenue Garnier, 69007, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Operational Team, ESA Platform, 31 Avenue Garnier, 69007, Lyon</wicri:regionArea>
<placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>GDS-France, 37 Rue de Lyon, 75012, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>GDS-France, 37 Rue de Lyon, 75012, Paris</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blanchard, Yannick" sort="Blanchard, Yannick" uniqKey="Blanchard Y" first="Yannick" last="Blanchard">Yannick Blanchard</name>
<affiliation wicri:level="3"><nlm:affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rose, Nicolas" sort="Rose, Nicolas" uniqKey="Rose N" first="Nicolas" last="Rose">Nicolas Rose</name>
<affiliation wicri:level="3"><nlm:affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herve, Severine" sort="Herve, Severine" uniqKey="Herve S" first="Séverine" last="Hervé">Séverine Hervé</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Simon, Gaelle" sort="Simon, Gaelle" uniqKey="Simon G" first="Gaëlle" last="Simon">Gaëlle Simon</name>
<affiliation wicri:level="3"><nlm:affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France. gaelle.simon@anses.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Ploufragan</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France. gaelle.simon@anses.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Veterinary research</title>
<idno type="eISSN">1297-9716</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term>
<term>France (MeSH)</term>
<term>Influenza A Virus, H1N1 Subtype (genetics)</term>
<term>Influenza A Virus, H1N1 Subtype (physiology)</term>
<term>Influenza A Virus, H1N2 Subtype (genetics)</term>
<term>Influenza A Virus, H1N2 Subtype (physiology)</term>
<term>Influenza A Virus, H3N2 Subtype (genetics)</term>
<term>Influenza A Virus, H3N2 Subtype (physiology)</term>
<term>Reassortant Viruses (physiology)</term>
<term>Sus scrofa (MeSH)</term>
<term>Swine (MeSH)</term>
<term>Swine Diseases (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term>
<term>France (MeSH)</term>
<term>Maladies des porcs (virologie)</term>
<term>Sous-type H1N1 du virus de la grippe A (génétique)</term>
<term>Sous-type H1N1 du virus de la grippe A (physiologie)</term>
<term>Sous-type H1N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H1N2 du virus de la grippe A (physiologie)</term>
<term>Sous-type H3N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H3N2 du virus de la grippe A (physiologie)</term>
<term>Suidae (MeSH)</term>
<term>Sus scrofa (MeSH)</term>
<term>Virus recombinants (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>France</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza A Virus, H1N2 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sous-type H1N2 du virus de la grippe A</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sous-type H1N2 du virus de la grippe A</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
<term>Virus recombinants</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza A Virus, H1N2 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
<term>Reassortant Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies des porcs</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Swine Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Sus scrofa</term>
<term>Swine</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>France</term>
<term>Suidae</term>
<term>Sus scrofa</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This report describes the detection of a triple reassortant swine influenza A virus of H1<sub>av</sub>
N2 subtype. It evolved from an avian-like swine H1<sub>av</sub>
N1 that first acquired the N2 segment from a seasonal H3N2, then the M segment from a 2009 pandemic H1N1, in two reassortments estimated to have occurred 10 years apart. This study illustrates how recurrent influenza infections increase the co-infection risk and facilitate evolutionary jumps by successive gene exchanges. It recalls the importance of appropriate biosecurity measures inside holdings to limit virus persistence and interspecies transmissions, which both contribute to the emergence of new potentially zoonotic viruses.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31590684</PMID>
<DateCompleted><Year>2020</Year>
<Month>02</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>02</Month>
<Day>04</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1297-9716</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>50</Volume>
<Issue>1</Issue>
<PubDate><Year>2019</Year>
<Month>Oct</Month>
<Day>07</Day>
</PubDate>
</JournalIssue>
<Title>Veterinary research</Title>
<ISOAbbreviation>Vet. Res.</ISOAbbreviation>
</Journal>
<ArticleTitle>Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.</ArticleTitle>
<Pagination><MedlinePgn>77</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1186/s13567-019-0699-y</ELocationID>
<Abstract><AbstractText>This report describes the detection of a triple reassortant swine influenza A virus of H1<sub>av</sub>
N2 subtype. It evolved from an avian-like swine H1<sub>av</sub>
N1 that first acquired the N2 segment from a seasonal H3N2, then the M segment from a 2009 pandemic H1N1, in two reassortments estimated to have occurred 10 years apart. This study illustrates how recurrent influenza infections increase the co-infection risk and facilitate evolutionary jumps by successive gene exchanges. It recalls the importance of appropriate biosecurity measures inside holdings to limit virus persistence and interspecies transmissions, which both contribute to the emergence of new potentially zoonotic viruses.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chastagner</LastName>
<ForeName>Amélie</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bonin</LastName>
<ForeName>Emilie</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>INRA, US 1426, GeT-PlaGe, 24 chemin de borde rouge - Auzeville, CS 52627, 31326, Castanet-Tolosan, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fablet</LastName>
<ForeName>Christelle</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Quéguiner</LastName>
<ForeName>Stéphane</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hirchaud</LastName>
<ForeName>Edouard</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lucas</LastName>
<ForeName>Pierrick</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gorin</LastName>
<ForeName>Stéphane</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barbier</LastName>
<ForeName>Nicolas</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Béven</LastName>
<ForeName>Véronique</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Garin</LastName>
<ForeName>Emmanuel</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Animal Health Service, Coop de France, 43 Rue Sedaine, 75538, Paris cedex 11, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Operational Team, ESA Platform, 31 Avenue Garnier, 69007, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>GDS-France, 37 Rue de Lyon, 75012, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Blanchard</LastName>
<ForeName>Yannick</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Viral Genetic and Biosecurity Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rose</LastName>
<ForeName>Nicolas</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Epidemiology, Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hervé</LastName>
<ForeName>Séverine</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Simon</LastName>
<ForeName>Gaëlle</ForeName>
<Initials>G</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0003-1099-5075</Identifier>
<AffiliationInfo><Affiliation>Swine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP53, 22440, Ploufragan, France. gaelle.simon@anses.fr.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Bretagne Loire University, Cité internationale, 1 place Paul Ricoeur, CS 54417, 35044, Rennes, France. gaelle.simon@anses.fr.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>259949</GrantID>
<Agency>FP7 Coordinated Action</Agency>
<Country></Country>
</Grant>
<Grant><GrantID>CF0010</GrantID>
<Agency>CoVetLab joint research project 2016</Agency>
<Country></Country>
</Grant>
<Grant><GrantID>643476</GrantID>
<Agency>European Union's Horizon 2020 program</Agency>
<Country></Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>10</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Vet Res</MedlineTA>
<NlmUniqueID>9309551</NlmUniqueID>
<ISSNLinking>0928-4249</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053118" MajorTopicYN="N">Influenza A Virus, H1N1 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057221" MajorTopicYN="N">Influenza A Virus, H1N2 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053122" MajorTopicYN="N">Influenza A Virus, H3N2 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016865" MajorTopicYN="N">Reassortant Viruses</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D034421" MajorTopicYN="N">Sus scrofa</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013552" MajorTopicYN="N">Swine</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013553" MajorTopicYN="N">Swine Diseases</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year>
<Month>05</Month>
<Day>29</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2019</Year>
<Month>09</Month>
<Day>23</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>10</Month>
<Day>9</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>10</Month>
<Day>9</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>2</Month>
<Day>6</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">31590684</ArticleId>
<ArticleId IdType="doi">10.1186/s13567-019-0699-y</ArticleId>
<ArticleId IdType="pii">10.1186/s13567-019-0699-y</ArticleId>
<ArticleId IdType="pmc">PMC6781375</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Emerg Infect Dis. 2010 Jan;16(1):96-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20031049</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1994 Jan;68(1):530-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8254767</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2008 Mar 07;5:40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18325125</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2018 Mar;216:142-152</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29519509</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2012 May 4;156(3-4):265-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22112856</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Sep 1;88(17):10110-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24965467</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Infect. 2015 Mar;143(4):772-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24977303</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Evol Appl. 2017 Oct 24;11(4):534-546</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29636804</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Res. 2013 Sep 04;44:72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24007505</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2019 Oct;25(10):1940-1943</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31538914</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Genet Med. 2008 Nov 27;3(1):158-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19565018</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Res. 2017 Oct 3;48(1):58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28974251</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2014 Jan;3(1):e5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26038494</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2011 Nov;85(21):11235-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21880744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2010 Jun 25;7(6):440-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20542248</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>mSphere. 2016 Dec 14;1(6):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27981236</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2017 Oct 19;12(10):e0185858</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29049305</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2014 Dec 26;9(12):e115815</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25542013</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 2012 Mar;157(3):555-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22198410</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2018 Jan 10;15(1):7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29316958</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genome Announc. 2013 Sep 19;1(5):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24051313</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2018 Nov 27;92(24):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30258006</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2015 Oct;89(19):9920-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26202246</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 2009;154(6):945-57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19458903</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Res. 2016 Aug 17;47(1):86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27530456</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Microbiol. 2013 Mar 23;162(2-4):543-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23201246</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2010 Jul;84(13):6769-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20410266</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Midi-Pyrénées</li>
<li>Occitanie (région administrative)</li>
<li>Rhône-Alpes</li>
<li>Région Bretagne</li>
<li>Île-de-France</li>
</region>
<settlement><li>Castanet-Tolosan</li>
<li>Lyon</li>
<li>Paris</li>
<li>Ploufragan</li>
<li>Rennes</li>
</settlement>
</list>
<tree><country name="France"><region name="Région Bretagne"><name sortKey="Chastagner, Amelie" sort="Chastagner, Amelie" uniqKey="Chastagner A" first="Amélie" last="Chastagner">Amélie Chastagner</name>
</region>
<name sortKey="Barbier, Nicolas" sort="Barbier, Nicolas" uniqKey="Barbier N" first="Nicolas" last="Barbier">Nicolas Barbier</name>
<name sortKey="Barbier, Nicolas" sort="Barbier, Nicolas" uniqKey="Barbier N" first="Nicolas" last="Barbier">Nicolas Barbier</name>
<name sortKey="Beven, Veronique" sort="Beven, Veronique" uniqKey="Beven V" first="Véronique" last="Béven">Véronique Béven</name>
<name sortKey="Beven, Veronique" sort="Beven, Veronique" uniqKey="Beven V" first="Véronique" last="Béven">Véronique Béven</name>
<name sortKey="Blanchard, Yannick" sort="Blanchard, Yannick" uniqKey="Blanchard Y" first="Yannick" last="Blanchard">Yannick Blanchard</name>
<name sortKey="Blanchard, Yannick" sort="Blanchard, Yannick" uniqKey="Blanchard Y" first="Yannick" last="Blanchard">Yannick Blanchard</name>
<name sortKey="Bonin, Emilie" sort="Bonin, Emilie" uniqKey="Bonin E" first="Emilie" last="Bonin">Emilie Bonin</name>
<name sortKey="Bonin, Emilie" sort="Bonin, Emilie" uniqKey="Bonin E" first="Emilie" last="Bonin">Emilie Bonin</name>
<name sortKey="Bonin, Emilie" sort="Bonin, Emilie" uniqKey="Bonin E" first="Emilie" last="Bonin">Emilie Bonin</name>
<name sortKey="Chastagner, Amelie" sort="Chastagner, Amelie" uniqKey="Chastagner A" first="Amélie" last="Chastagner">Amélie Chastagner</name>
<name sortKey="Fablet, Christelle" sort="Fablet, Christelle" uniqKey="Fablet C" first="Christelle" last="Fablet">Christelle Fablet</name>
<name sortKey="Fablet, Christelle" sort="Fablet, Christelle" uniqKey="Fablet C" first="Christelle" last="Fablet">Christelle Fablet</name>
<name sortKey="Garin, Emmanuel" sort="Garin, Emmanuel" uniqKey="Garin E" first="Emmanuel" last="Garin">Emmanuel Garin</name>
<name sortKey="Garin, Emmanuel" sort="Garin, Emmanuel" uniqKey="Garin E" first="Emmanuel" last="Garin">Emmanuel Garin</name>
<name sortKey="Garin, Emmanuel" sort="Garin, Emmanuel" uniqKey="Garin E" first="Emmanuel" last="Garin">Emmanuel Garin</name>
<name sortKey="Gorin, Stephane" sort="Gorin, Stephane" uniqKey="Gorin S" first="Stéphane" last="Gorin">Stéphane Gorin</name>
<name sortKey="Gorin, Stephane" sort="Gorin, Stephane" uniqKey="Gorin S" first="Stéphane" last="Gorin">Stéphane Gorin</name>
<name sortKey="Herve, Severine" sort="Herve, Severine" uniqKey="Herve S" first="Séverine" last="Hervé">Séverine Hervé</name>
<name sortKey="Herve, Severine" sort="Herve, Severine" uniqKey="Herve S" first="Séverine" last="Hervé">Séverine Hervé</name>
<name sortKey="Hirchaud, Edouard" sort="Hirchaud, Edouard" uniqKey="Hirchaud E" first="Edouard" last="Hirchaud">Edouard Hirchaud</name>
<name sortKey="Hirchaud, Edouard" sort="Hirchaud, Edouard" uniqKey="Hirchaud E" first="Edouard" last="Hirchaud">Edouard Hirchaud</name>
<name sortKey="Lucas, Pierrick" sort="Lucas, Pierrick" uniqKey="Lucas P" first="Pierrick" last="Lucas">Pierrick Lucas</name>
<name sortKey="Lucas, Pierrick" sort="Lucas, Pierrick" uniqKey="Lucas P" first="Pierrick" last="Lucas">Pierrick Lucas</name>
<name sortKey="Queguiner, Stephane" sort="Queguiner, Stephane" uniqKey="Queguiner S" first="Stéphane" last="Quéguiner">Stéphane Quéguiner</name>
<name sortKey="Queguiner, Stephane" sort="Queguiner, Stephane" uniqKey="Queguiner S" first="Stéphane" last="Quéguiner">Stéphane Quéguiner</name>
<name sortKey="Rose, Nicolas" sort="Rose, Nicolas" uniqKey="Rose N" first="Nicolas" last="Rose">Nicolas Rose</name>
<name sortKey="Rose, Nicolas" sort="Rose, Nicolas" uniqKey="Rose N" first="Nicolas" last="Rose">Nicolas Rose</name>
<name sortKey="Simon, Gaelle" sort="Simon, Gaelle" uniqKey="Simon G" first="Gaëlle" last="Simon">Gaëlle Simon</name>
<name sortKey="Simon, Gaelle" sort="Simon, Gaelle" uniqKey="Simon G" first="Gaëlle" last="Simon">Gaëlle Simon</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeFranceV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000012 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000012 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeFranceV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:31590684
   |texte=   Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:31590684" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeFranceV1

This area was generated with Dilib version V0.6.35.
Data generation: Sun Aug 9 07:31:43 2020. Site generation: Thu Mar 25 22:05:26 2021

	Serveur d'exploration sur la grippe en France
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la grippe en France

Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.

Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki